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1.
Molecules ; 28(9)2023 Apr 28.
Article in English | MEDLINE | ID: covidwho-2319471

ABSTRACT

The potential of natural products from both plant and animal sources to treat diseases remains enormous, as our understating forms just the tip of the iceberg [...].


Subject(s)
Biological Products , Animals , Biological Products/pharmacology , Biological Products/therapeutic use , Plants , Plant Extracts
2.
Molecules ; 27(7)2022 Apr 01.
Article in English | MEDLINE | ID: covidwho-1776290

ABSTRACT

Many mushroom species are consumed as food, while significant numbers are also utilised medicinally. Mushrooms are rich in nutrients and bioactive compounds. A growing body of in vitro, in vivo, and human research has revealed their therapeutic potentials, which include such properties as anti-pathogenic, antioxidant, anti-inflammatory, immunomodulatory, gut microbiota enhancement, and angiotensin-converting enzyme 2 specificity. The uses of medicinal mushrooms (MMs) as extracts in nutraceuticals and other functional food and health products are burgeoning. COVID-19 presents an opportunity to consider how, and if, specific MM compounds might be utilised therapeutically to mitigate associated risk factors, reduce disease severity, and support recovery. As vaccines become a mainstay, MMs may have the potential as an adjunct therapy to enhance immunity. In the context of COVID-19, this review explores current research about MMs to identify the key properties claimed to confer health benefits. Considered also are barriers or limitations that may impact general recommendations on MMs as therapy. It is contended that the extraction method used to isolate bioactive compounds must be a primary consideration for efficacious targeting of physiological endpoints. Mushrooms commonly available for culinary use and obtainable as a dietary supplement for medicinal purposes are included in this review. Specific properties related to these mushrooms have been considered due to their potential protective and mediating effects on human exposure to the SARS CoV-2 virus and the ensuing COVID-19 disease processes.


Subject(s)
Agaricales , COVID-19 Drug Treatment , Dietary Supplements , Functional Food , Humans , Immunomodulation
3.
Molecules ; 26(17)2021 Sep 01.
Article in English | MEDLINE | ID: covidwho-1436074

ABSTRACT

Nutraceutical, a term derived from 'nutrition' and 'pharmaceutical', refers to any product isolated from herbs, nutrients, specific diets, processed foods, and beverages used not only for nutritional but also for medicinal purposes [...].


Subject(s)
Communicable Diseases/immunology , Dietary Supplements , Gastrointestinal Diseases/immunology , Inflammation/immunology , Neoplasms/immunology , Nutritional Status/immunology , Humans
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